Furthermore, CD3/Fn14 BiTE [89], CD3/B7-H3 BiTE [90], CD3/EGFR BiTE, and CD3/IL13Rα2 BiTE [91] have also shown promising results in preclinical studies of glioblastoma and hepatocellular carcinoma (HCC). The gene discussed is TNFRSF12A; the disease is hepatocellular carcinoma.