DDX5 and Infertility: The authors demonstrated that (i) germ cell-specific DDX5 KO (DDX5-/-) leads to infertility in adult male mice due to the complete elimination of germ cells [136]; (ii) male germ cells gradually disappeared in DDX5(-/-) mice from E18.5 to P6 [136]; and (iii) DDX5 ablation impeded the proliferation of gonocytes [136].