The results displayed that the risk score was negatively correlated with immune infiltration score (Stromal score, Immune score and ESTIMATE score) (Fig. 7A, B); furthermore, the risk score was negatively correlated with tumor-infiltration lymphocytes (TILs) (such as CD4 + T cells, NK, and CD8 + T cells) (Fig. 7C, D). This evidence concerns the gene CD4 and neoplasm.