ELANE and autoimmune disease: The GSEA results indicated that the gene sets in the ELANE high-expression group were primarily involved in the signaling pathways correlated with the regulation of immune response, such as the chemokine signaling pathway, leukocyte transendothelial migration, cytokine-cytokine receptor interaction, infection, cell adhesion molecules, and autoimmune diseases (Fig. 7A–H and Table 2).