IFNG and COVID-19: The intensity of CoVac-1-induced IFN-γ T-cell responses in B-cell deficient patients at day 28 (B-CoVs, median calculated spot count 144) was similar or even higher than T-cell responses to CoVac-1 peptides (median calculated spot count 55), to SARS-CoV-2-specific (median calculated spot count 61) and to cross-reactive (median calculated spot count 105) T-cell epitopes9,10 in immunocompetent healthy COVID-19 convalescents (HCs), with asymptomatic and mild disease9,17 (Fig. 5e, Supplementary Table 6).