PDGFRB and intrahepatic cholangiocarcinoma: Multiplex-IF of intrahepatic cholangiocarcinoma (Supplementary Fig. 7g) revealed stromal protein gradients similar to those observed in CRLM, which were characterized by ASMA, NGFR, and PDGFRa at the outer edge, and FAP and PDGFRb at the inner side of the rim (Fig. 5e).