ALDH1L1 and cancer: Therefore, there is a possibility that not only HuH-7 cells but also other cancer cell lines respond to ZMP depending on the expression level of ALDH1L1. Interestingly, in the PRISM repurposing primary screen data set, cordycepin, which is also an AMP analog, was the most sensitive compound in the low ALDH1L1 expression group [q-value < 0.0001] (Fig. 5B).