INHBE and preeclampsia: Activins and inhibins, members of the TGF-β superfamily, and follistatin isoforms, their regulatory proteins, have been found ubiquitously expressed in placental tissues and seem to play a crucial role in extravillous trophoblast invasion and spiral arteries remodelling during early placental development [13], suggesting a plausible dysregulation in maternal serum across preeclampsia.