AMH and lung carcinoma: Studies using lung cancer epithelial cells reported a crosstalk between AMHR2 and BMPR2 causing enhanced SMAD2/3 phosphorylation upon loss of AMH or AMHR2,131 possibly via mixed-heteromeric receptor complexes driven by BMP ligands.93 Correspondingly, in these cancerous epithelial cells, siRNA depletion of AMH or AMHR2 drives EMT,131 suggesting inhibitory functions of AMH in EMT.