MAPT and Mental deterioration: The pathologic features of tau‐AC‐injected mouse brains were highly consistent with previous studies reporting a clear correlation between neurofibrillary tangle deposits and cognitive decline.[41] This current study also demonstrated that tau‐AC resulted in multiple pathological processes not only in primary neurons (i.e., impaired AIS dynamics and tau trafficking) but also in mice (i.e., defective memory retrieval).