Likewise, compromising the function of LONP1, another mitochondrial protease whose inhibition has been reported to cause the death of lymphoma cells [65], or of PMPCA, a subunit of the mitochondrial processing peptidase (MPP) complex [11] which we had identified in an earlier screen for proteases potentially relevant in non-apoptotic cell death, did not affect parthanatic cell death. The gene discussed is PMPCA; the disease is lymphoma.