Considering the observation that patients with functional seizures (psychogenic nonepileptic seizures/attacks) have significantly increased basal diurnal cortisol levels,6 the potential role of HPA axis in FND,7 the observation that NR3C1 gene provides negative feedback to the HPA axis,9 and the observed associations between rs41423247 in the NR3C1 gene and psychopathologies,9, 10 we aimed to investigate the association between NR3C1 rs41423247 polymorphism and functional seizures (psychogenic nonepileptic seizures/attacks) in a case–control study. Here, NR3C1 is linked to Seizure.