RORC and Hepatitis: On days 5 and 15 PI, Th17 mRNA and IL17A expression levels were elevated, similarly in S. mansoni-infected mice, in which the liver developed significant hepatic granulomatous inflammation, with higher expression levels of IL17 and RORC, suggesting that its lesions may be associated with IL17 produced by Th 17 cells (Kalantari et al., 2019).