SPI1 and infection: There are relationships between Th1/Th2/Th17/Treg/Th9/Th21 transcriptional factors with their cytokine lineages, where positive correlations (r ≥ 0.8) were found between RORC and IL17A, SPI1 and IL9, and BCL6 and IL21 in the experiment groups throughout the whole period of infection as shown in Table 2.