Both mainly consisted in NK cells with phenotype CD56+CD16highCD45RA+ CD107a+ and tumor markers expression (Table S1), Metacluster-8 was found enriched in BC patients in comparison with healthy controls and contained CD45RO+ cells (10.7% versus 6.9% of control, p<0.05) (Figure 6B). This evidence concerns the gene LAMP1 and neoplasm.