INS and Hypoglycemia: We searched the electronic databases including PubMed, Medline, Scopus, Cochrane Review, and Google Scholar up to September 2020 using the MeSH term and keywords “type 1 diabetes or insulin dependent diabetes mellitus”, “Technology”, “pump or CSII or insulin pump therapy”, “continuous or flash glucose monitor”, “glucose monitoring system”, “hypoglycemia”, “fear of hypoglycemia”, “distress or worry”, “quality of life” combined with the Boolean operators “AND” “OR”.