Our analysis indicated that CTLA-4, HAVCR2, LAG3, PDCD1, PDCD1LG2 and TIGIT were significantly enriched in the high-infiltration group, but CD274, an inhibitory marker expressed mainly on surfaces of tumor cells and macrophages, was not significantly enriched(42) (Figure 6K). Here, PDCD1LG2 is linked to neoplasm.