MICU1 and familial dilated cardiomyopathy: Immunofluorescence staining showed that endothelial-specific overexpression of MICU1 inhibited DCM-induced apoptosis in both total cells and CMECs (Fig. 7A, B, C), improved microvascular barrier function, and ameliorated vascular permeability in myocardial tissue sections of diabetic mice (Fig. 7D-I).