Given that in our functional adhesion experiments, we found no difference in adhesion strength when we treated ECs alone or when we co-treated ECs and NGs, and that the pattern of surface adhesion molecules of NGs was very similar in C1-INH-HAE patients and in controls, we can anticipate that treatments affected mostly the adhesion properties of ECs and not those of NGs. Here, SERPING1 is linked to hereditary angioedema.