TAAR1 and Glucose intolerance: Notably, genetic ablation of Taar1 significantly suppressed the expression of Taar1 in metabolic tissues (p < 0.001 in all cases, Fig. 6G) and protected against tryptamine and phenethylamine-induced glucose intolerance and insulin resistance in mice (p < 0.05 in all cases, Fig. 6H–K).