Of note, we did not find a consistent down-regulation of CXCL12 in sorted MM cells from focal lesions using ELISA (n = 6 patients, mean ratio RBM/FL: 1.26, (range: 0.91–1.75), p = 0.46 in linear mixed-effects model, Supplementary Fig. 5g). The gene discussed is CXCL12; the disease is Miyoshi myopathy.