FGF2 and neoplasm: We further verified the in vivo relevance of the anti-angiogenic effect of VEGF-B using murine T241 fibrosarcoma cells expressing a high level of FGF2 (T241-FGF2, Fig. 6a) and investigated tumor angiogenesis and tumor growth in Vegf-b−/− mice (produced by the Jackson Laboratory, https://www.komp.org/, Supplementary Fig. 15a, b).