These included known AF genes, TBX5 (PIP 0.99), NKX2-5 (0.99), PITX2 (0.99), ZFHX3 (0.85) and GATA4 (0.57), as well as TFs with roles in heart development such as HAND2 (0.87), ZEB2 (0.98), and PRRX1 (0.72). This evidence concerns the gene ZEB2 and atrial fibrillation.