MPO and inflammatory bowel disease: Neutrophils, the most abundant type of leukocytes in blood, play a crucial role in promoting thrombosis via NETs formation,[24] and there was a higher level of plasma NETs in patients with active IBD than in healthy participants.[14, 25] Therefore, we evaluated whether the level of plasma NETs was elevated in the DSS‐treated mice and found that MPO‐DNA complexes, as markers of NETs, were significantly increased in the DSS‐treated group when compared to control group (Figure 1j).