For example, messenger RNA expression is similarly up- or down-regulated in some genes (e.g., AKT3, CCNE1, MYC, RB1) and high mutation rates in specific genes (e.g., BRCA1, RB1, TP53) are observed in both TNBC and ovarian cancer [28, 29]. Here, AKT3 is linked to ovarian carcinoma.