Since METTL3c was largely absent within endogenous METTL3, combined with data from m6A dot blots and tumor cell growth assays showing that METTL3-2MA functioned similarly to METTL3-WT (Figure 2—figure supplement 2h–l), we did not investigate METTL3c in the following study. This evidence concerns the gene METTL3 and neoplasm.