CD4 and HIV-1 infection: In control experiments, HIV-1 infectivity was notaffected by BafA1, consistent with the pH-independence of HIV-1 Env-mediatedmembrane fusion.5 In contrast to TZM-blcells, HIV-1 infection of primary human CD4+ T-cells was inhibitedby ∼40% with EIPA and by ∼60% and ∼75% with Pitstop2and Dynasore, respectively (Figure 8F).