The expression levels of TLR2, TLR4, BCR, CD19, PI3K, PIP3, AKT, PDK1, PKCs, PKN, and eNOS in oral cancer samples were higher than those in normal samples, and the overexpression samples were higher than those in oral cancer samples, and the expression levels after knockdown were lower than those in oral cancer samples and overexpression samples (Figure 12). Here, PDK1 is linked to lip and oral cavity carcinoma.