Similarly, in our work, we found high CXCR4 and CXCR7 levels in the placental tissues of puerperae with placenta previa, and silencing of CXCR4 and CXCR7 led to diminished HTR8/SVneo cell proliferative, migratory, and invasive capabilities. The gene discussed is CXCR4; the disease is placenta praevia.