In this study, with the help of the CIBERSORT database, we explored the infiltration levels of 22 immune cell types in BLCA, TAMs and TILs were its main immune cell types, 12 of which were immune cell subtypes associated with overall survival of BLCA patients, M2-macrophages were risk factors for overall survival of BLCA patients, and CD8+ T cells were the protective factors, which is consistent with numerous researchers. Here, CD8A is linked to bladder transitional cell carcinoma.