NFKB1 and urinary bladder cancer: In the gene enrichment analysis of the most relevant signature module genes obtained from WGCNA analysis for each risk group and differential genes in ICIs-responding patients, we found that they were enriched in signaling pathways such as NF-KB signaling pathway, JAK-STAT pathway, and Wnt pathway, which suggested that the above signaling pathways might be related to bladder cancer drug resistance and recurrence.