Interestingly, GWAS associations in Aged TBI 1 month post injury reveals a significantly altered genomic network pattern, where Alzheimer’s related genes FOS8, MPZL1, LIMS2, ELL, EXOC3L2, STK11, TOP1, CDC5L, ABCA1, and KANSL1 are linked to neurodegeneration, inflammation, Parkinson’s, stroke and dementia. The gene discussed is LIMS2; the disease is stroke disorder.