Examples of this include HER2 amplification in breast cancer (Paik et al, 2008), EGFR amplification in gliomas (Smith et al, 2001; preprint: Ni et al, 2022), and MET amplification in non‐small‐cell lung cancer (NSCLC; Drilon et al, 2017a). The gene discussed is EGFR; the disease is central nervous system cancer.