Tumor-related signaling pathways were mainly concentrated in cancer (18 h, 24 h, 3 d and 7 d), chemical carcinogenesis (18 h, 24 h and 7 d), PI3K-Akt (18 h, 24 h, 3 d and 7 d), hepatocelleular carcinoma (18 h) and p53 (3 d). The gene discussed is AKT1; the disease is neoplasm.