RHOC and infection: On the 3rd day of infection, the CCs of cell division site and cell surface furrow, MFs of GTPase activity and GTP binding, and BPs of epiboly involved in wound healing, wound healing, spreading of cells and mitotic cytokinetic process were mainly triggered because of the high expression of Ras- and Rho-related proteins (e.g. Rhoa, Rhoc, Rab11a and Rab11b) (Fig. 5c–e).