IL1B and osteoarthritis: In order to investigate the specific mechanism of the effect of DDX3X gene regulated by miR-181-5p on osteoarthritis, chondrocytes in inhibitor NC, inhibitor miR-181a-5p and inhibitor miR-181a-5p + si-DDX3X groups were stimulated with 10 μg/mL of IL-1β, and the cells were collected to detect the expression of proteins related to NF-κB signal pathway.