Depletion of eosinophils in ApcMin/+ (ApcMin/+/ΔdblGATA) mice cut their survival in half compared to the ApcMin/+ control group, and the subsequent depletion of CD8 + T cells caused another 16% drop in ApcMin/+/ΔblGATA survival and increased tumor burden, which indicated a synergistic yet CD8 + T cell-independent anti-tumor effect from activated eosinophils. Here, CD8A is linked to neoplasm.