AHR and infection: Indeed, unsupervised hierarchical clustering stratifies WT and ECΔAhr endothelial samples into three main clusters according to infection status and level of AHR activity: 1) uninfected WT (strongest AHR signature), 2) infected WT and uninfected ECΔAhr (dampened AHR signature), and 3) infected ECΔAhr (weakest AHR signature) (Fig. 4c).