AHR and infection: While suppression of AHR signalling may exacerbate lung damage, it is important to note that protective AHR signalling in lung endothelial cells is not completely lost following infection, as infected ECΔAhr mice exhibit further decreased AHR signalling (Fig. 4c and Extended Data Fig. 5) and have increased lung vascular leakage (Fig. 2j, k), relative to infected WT controls.