As demonstrated in Fig. 5B, the cell abundance of resting dendritic cells, M0 and M2 macrophages, gamma-delta (γδ) T cells, Tregs, naive CD4 T cells, follicular helper T cells (Tfh), monocytes, Naive B cells, memory b cells, resting mast cells, eosinophils, and resting NK cells were affected by TSPAN expression, demonstrating that the TSPAN family is closely associated with the immune infiltration of GBM. The gene discussed is CD4; the disease is glioblastoma.