There was no correlation between all studied parameters and clinicopathological data (age, HB, RBCs, PLT, WBCs and tumor size) in CRC, and non-cancer patient, except significant negative correlations between circ-SAMARCA5, circ-NOL10 and PLT in piles (P = 0.038, 0.025 respectively), circ-LDLRAD3 and age in CRC (P = 0.015), while a positive significant correlation between CEA and PLT in piles (P = 0.048). The gene discussed is CEACAM5; the disease is colorectal carcinoma.