MiR-181b-5p or miR-17-3p diminished the inhibitory impact of circ-SMARCA5 on tumor cell, confirming that circ-SMARCA5 could sponge miR-181b-5p, as well as miR-17-3p, to induce TIMP3 and suppress malignant behaviors12,13. Here, TIMP3 is linked to neoplasm.