Anti‐inflammatory drugs have the ability to rapidly modify the tumor immune microenvironment, thereby enhancing immunogenicity.[38] For example, in blunt trauma patients, the expression of IL‐1 in CXCR2+ lung neutrophils could be induced by IL‐5 expression by innate lymphocytes, culminating in early lung injury.[39] Moreover, in patients with metastatic pediatric sarcomas the elevated levels of serum CXCR2 ligands and CXCL8 are associated with reduced survival rates. This evidence concerns the gene CXCR2 and neoplasm.