For the index SNP at the APOL1 locus found in this GWAS (rs2239785), we saw an association with diabetic maculopathy with the same direction of effect as the primary DME GWAS (OR = 1.17, P = 5.5x10-5, MAFcases = 0.18, MAFcontrols = 0.16; N = 2,790 cases, 284,826 controls). This evidence concerns the gene APOL1 and diabetic maculopathy.