To investigate if these six candidate microRNAs identified by the luciferase reporter gene assay to bind to the HspB5 UTR are able to regulate endogenous HspB5, we transiently transfected the respective oligonucleotide mimics into rat C6 glioma cells and measured their influence on the amount of HspB5 protein. Here, CRYAB is linked to central nervous system cancer.