AKT1 and non-small cell lung carcinoma: Moreover, aberrant activation of the phosphoinositide‐3‐kinase (PI3K)‐protein kinase B (Akt)‐mTORC1 signaling pathway is frequently observed in NSCLC secondary to activating mutations in the epidermal growth factor receptor, Kristen rat sarcoma viral oncogene homolog, or PI3K subunits [9, 10].