IL6 and Mental deterioration: In the Northern Manhattan Study, higher levels of IL‐6 were associated with a global measure of cognition (Mini‐Mental State Examination total scores) and with cognitive decline (Economos et al., 2013), while no association was observed for IL‐1, IL‐2, TNF‐α, and the corresponding receptors IL‐2R, TNFR‐1, and TNFR‐2 (Wright et al., 2006).