Initially associated with oligodendrocyte function (Emery et al., 2009), MYRF is widely expressed and has recently been associated with CHD (Garnai et al., 2019; Hamanaka et al., 2019; Homsy et al., 2015; Jin et al., 2017; Lonsdale et al., 2013; Qi et al., 2018). This evidence concerns the gene MYRF and coronary artery disorder.