NPHP1 and autosomal dominant polycystic kidney disease: Indeed, they continued to express markers of early development and dedifferentiation, such as Pax2, in both ADPKD and NPHP1 patients (Murer et al., 2002; Stayner et al., 2006; Grimley and Dressler, 2018), as also found in NPHP1 mice (Supplementary Figures S3A, B).