Levels of NQO1 mRNA were negatively correlated with endothelial in lung squamous cell carcinoma, pancreatic adenocarcinoma, and rectum adenocarcinoma and positively correlated with glioma, brain lower grade glioma, testicular germ cell tumors, thyroid carcinoma, and thymoma (Figure 4A), which illustrates that NQO1 has different regulatory patterns in various types of cancer. Here, NQO1 is linked to central nervous system cancer.