Microsatellite instability was positively correlated with the NQO1 mRNA expression levels in esophageal carcinoma and uveal melanoma and negatively correlated with uveal melanoma, invasive breast carcinoma, pan-kidney cohort, prostate adenocarcinoma, and ovarian serous cystadenocarcinoma (Figure 3B). The gene discussed is NQO1; the disease is invasive breast carcinoma.