NQO1 and cancer: NAD(P)H: Quinone Oxidoreductase 1 (NQO1) is a flavoenzyme that can be upregulated by the transcription factor nuclear factor erythroid 2-related factor 2 (NRF2), which plays important roles in cell detoxification, cancer cell growth, and immune response (Awadallah et al., 2008; Kasai et al., 2016).