MTHFR and hydrops fetalis: A significantly (FDR < 0.05) increased expression of ALKBH5, VIRMA, KMT2E, and HDAC2, whereas, reduced expression and KDM4B, H2AW, H2BC8, H3C1, MTHFR, and CMBL were found in the HF patients compared to the control group (Figure 1).