A significantly (FDR < 0.05) increased expression of ALKBH5, VIRMA, KMT2E, and HDAC2, whereas, reduced expression and KDM4B, H2AW, H2BC8, H3C1, MTHFR, and CMBL were found in the HF patients compared to the control group (Figure 1). The gene discussed is H2AC25; the disease is hydrops fetalis.