APOB and periodontitis: MVMR-IVW estimate showed that apo A1 (OR=0.72, 95% CI=0.36–1.41, P-value=0.34), apo B (OR=1.99, 95% CI=0.68–5.86, P-value=0.21), HDL-C (OR=1.38, 95% CI=0.68–2.81, P-value=0.37), LDL-C(OR=0.57, 95% CI=0.20–1.66, P-value=0.30) and TG (OR=0.94, 95% CI=0.69–1.29, P-value=0.71) were not significantly associated with the risk of periodontitis (Figure 4).