Based on the multivariable Cox regression for CSS, tumor grade (β = 0.46; HR = 1.59), AJCC T stage, (β = 0.31; HR = 1.36), AJCC N stage (β = 0.32; HR = 1.38), chemotherapy (β = -0.98; HR = 0.38), CEA (β = 0.26; HR = 1.30), and liver metastasis (β = 0.60; HR = 1.82) were deemed to be significantly associated with the CSS in the development set (Table 2). Here, CEACAM5 is linked to neoplasm.