Based on the multivariable Cox regression for OS, tumor grade (β = 0.48; HR = 1.62), AJCC T stage, (β = 0.30; HR = 1.35), AJCC N stage (β = 0.26; HR = 1.30), chemotherapy (β = -1.01; HR = 0.37), CEA (β = 0.25; HR = 1.28), and liver metastasis (β = 0.58; HR = 1.79) were deemed to be significantly associated with the OS in the development set. Here, CEACAM5 is linked to neoplasm.