Moreover, as expected, three-vessel CAD patients had more marked LV systolic dysfunction as assessed by echocardiography, were taking more drugs, such as ACE inhibitors, nitrates, insulin, aspirin, and statins, more frequently underwent coronary artery bypass graft surgery as a method of revascularization, and more likely experienced a previous MI (p < 0.05). Here, INS is linked to myocardial infarction.