YAP1 and neoplasm: During the tumor “shutdown” phase, which was initiated at day 14 of tumor induction and lasted until day 38 (Supplementary Fig. 3a), triglycerides and glucose partially returned to control levels, while the reduction in protein content in thoraces was halted, indicating that the systemic effects of yki-tumors were ameliorated (Supplementary Fig. 3b–d).